“Life, liberty, and the pursuit of happiness:” some people might argue that the U.S. Constitution endorses hedonism, and indeed many politicians want to ignore or get rid of the Constitution, but not necessarily because of hedonism. We should not be dismissive about encouraging people to pursue happiness. Happiness can be good for your brain. Depression is surely bad for your brain.

Positive mood states promote more effective thinking and problem solving. A recent scholarly report[1]reviews the literature demonstrating that positive mood broadens the scope of attentiveness, enhances semantic associations over a wide range, improves task shifting, and improves problem-solving capability. The review also documents the changes in brain activation patterns induced by positive mood in subjects while solving problems. Especially important is the dopamine signaling in the prefrontal cortex.

Published studies reveal that a variety of techniques are used to momentarily manipulate mood. These have included making subjects temporarily happy or sad by asking subjects to recall emotionally corresponding past experiences or to view film clips or hear words that trigger happy or sad feelings,

The effect of happiness on broadened attentiveness arises because the brain has better cognitive flexibility and executive control, which in turn makes it easier to be more flexible and creative. Happy problem solvers are better able to select and act upon useful solutions that otherwise never consciously surface. Happiness reduces perseverative tendencies for errant problem-solving strategies. The broadened attentiveness, for example, allows people to attend to more stimuli, both in external visual space and in internal semantic space, which in turn enables more holistic processing. For example, in one cited study, experimenters manipulated subjects’ momentary mood and then measured performance on a task involving matching of visual objects based on their global versus local shapes. Happy moods yielded better global matching.

Other experiments report broader word association performance when subjects are manipulated to be happier. For example, subjects in a neutral mood would typically regard the word “pen” as a writing tool and would associate it with words like pencil or paper. But positive mood subjects would think also of pen as an enclosure and associate it with words like barn or pigs. This effect has been demonstrated with practical effect in physicians, who, when in a happy mood, thought of more disease possibilities in making a differential diagnosis.

The review authors reported their own experiment on beneficial happy mood effects on insightfulness, using a task in which subjects were given three words and asked to think of a fourth word that could be combined into a compound word or phrase. For example, an insightful response to “tooth, potato, and heart” might be “sweet tooth, sweet potato, and sweetheart.” Generating such insight typically requires one to suppress dominant “knee jerk” responses such as associating tooth with pain and recognizing that pain does not fit potato while at the same time becoming capable of switching to non-dominant alternatives.

Other cited experiments showed that happy mood improved performance on “Duncker’s candle task.”  Here, subjects are given a box of tacks, a candle, and a book of matches, and are asked to attach a candle to the wall in a way that will burn without dripping wax on the floor. Subjects in a happy mood were more able to realize that the box could be a platform for the candle when the box is tacked to the wall.  

Such effects of happy moods seem to arise from increased neural activity in the prefrontal cortex and cingulate cortex, areas that numerous prior studies have demonstrated as crucial parts of the brain’s executive control network. Similar effects have been observed in EEG studies. Other research suggests that the happiness effect is mediated by increased release of dopamine in the cortex that serves to up-regulate executive control.

The review authors described a meta-analysis of 49 positive-psychology manipulation studies showing that momentary happiness is readily manipulated by such strategies as deliberate optimistic thinking, increased attention to and memory of happy experiences, practicing mindfulness and acceptance, and increasing socialization. The effect occurs in most normal people and even in people with depression, anxiety, and schizophrenia. Biofeedback training, where subjects monitor their own fMRI scans or EEGs, might be an even more effective way for people to train themselves to be happier.

The main point is that people can be as happy as they choose to be.

For more on how positive mood influences memory ability,

see my new book, Memory Power 101 (http://skyhorsepublishing.com).

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[1]Subramaniam, K. and Vinogradov, S. (2013). Improving the neural mechanisms of cognition through the pursuit of happiness. Frontiers in Human Neuroscience. 7 August. Doi: 10.3389/fnhum.2013.00452

In other blog posts I have explained why sleep is good for the brain in general and memory formation in particular. Now a new discovery provides another reason for people to get enough sleep. The study examined a type of support cell in the brain, oligodendrocytes–let’s call them oligos for short. These cells wrap their membranes around nerve cells to form what is called myelin, which forms an electrical insulation in a way that speeds up the propagation of nerve impulses through neural networks. You may have heard about oligos in reading about multiple sclerosis, a disease that impairs nerve communication because oligos die and the myelin insulation degrades.

Speed of transmission is important–it influences IQ for example. As you know from buying a new computer, the faster processor speed gives it new capabilities your old clunker could not do. A similar idea applies to the brain.

Anyway, this new study, from the University of Wisconsin, focused on oligos because other research had shown that sleep promoted the expression of several genes that are involved in synthesis of cell membranes in general and those in oligos in particular. Unlike neurons, oligos die, and are replaced in the brain. Thus, anything that affects their turnover is important for brain function. Sleep has been implicated in this turnover because a common neurotransmitter in the brain, glutamate, is known to increase in wakefulness and decline during sleep. Glutamate  suppresses maturation of oligo precursor cells into formation of myelin insulation.

In this particular study, investigators examined a genome-wide profile of oligo gene expression in mice after a 6-7 hour periods of sleep or spontaneous wakefulness, or four hours of forced wakefulness (sleep deprivation). They found that 357 genes were expressed differently, depending on the time of day, in response to normal daily rhythms. More dramatic was the observation that 714 genes changed expression in conjunction with the sleep/wakefulness cycle, independent of the time of day. Of these genes, 310 were “sleep” genes that were selectively activated during sleep.

Many of the sleep genes contribute to maturation of oligos into myelin. In follow up experiments, mice were injected with a radiolabeled tag that marks the birth of new cells. Injection occurred eight hours before mice spent a long period of either of wakefulness or sleep. The number of newly born oligos was almost double in the sleep group compared to the wake group. More detailed analysis showed that this increase was specifically correlated with the amount of REM sleep (dream sleep in humans).

This REM effect may have particular importance in humans. Most REM sleep occurs in the early morning hours and only after substantial time has been spent in non-REM stages of sleep. Thus, cutting a night’s sleep short by getting up early may decrease the amount of REM time and thus the beneficial effects on oligo proliferation. So don’t feel guilty about “sleeping in” from time to time.

We might also think about how these findings could have special relevance to children, whose brains are incompletely myelinated. Getting children up early in the morning to start school at 8 AM may not be such a good idea. Until school districts get around to changing school hours, you might tell you kids about my learning and memory improvement e-book, Better Grades, Less Effort, available at Smashwords.com.

Source:

Bellesi, M., et al. (2013) Effects of sleep and wake on oligodendrocytes and their precursors. J. Neuroscience. 33 (36), 14288-14300.

Most people now have been told that mental activity is good for the brain. I have even posted information that it can build “cognitive reserve” that can delay or reduce the symptoms of Alzheimer’s disease. Therefore, it would be no surprise if popularity increased for mentally stimulating games like crossword puzzles, Sudoko, bridge, dominoes, chess, and the like.

In addition to these traditional games, another form of mental stimulation is to learn mnemonic techniques, such as creating associations with mental images, acrostics, acronyms, the method of loci, mental imaging of peg-words, and the like, which I explain in my books, Memory Power 101 and Better Grades, Less Effort. While these techniques are task specific, mastering them can produce benefits that last beyond the time when you are using these mnemonics. For example, when I was in high school, I used to give memory demonstrations using a well-known image-word peg system. Even when I quit doing that, my general capacity for remembering remained better than before because my brain had been trained to be more agile and imaginative in generating images that I could use in making memory associations. My mind was also probably more disciplined.

The scientific basis for such claims is solid. Numerous research reports confirm that even older people can improve their memory skills with instruction and practice.[1] Even with traditional memory training, research has shown that by teaching people multiple strategies, the training benefit can be seen immediately, can endure for up to five years, and even transfer to everyday learning tasks.

The scientific explanation is straightforward. When the brain is challenged to solve problems and enhance memory capability, the neurons have to grow new contact points among neurons. This process requires new protein synthesis, growth of neuron terminals, and boosting of neurotransmitter systems. In other words, mental challenge changes the brain physically. Through training, you can sculpt a more alert, focused, and smarter brain.

As a result of this understanding, a host of mental training options have become available. The hype often seems to sound like snake oil, but some training programs are documentably effective. For example, we know from published research that I have described before that working memory capacity can be extended by formal training and that IQ increases as a result.

A new emphasis seems to be emerging to create training platforms that are cost effective, self-administered, flexible, and easily distributed to wide segments of population. CD, audiotape, and web-based approaches can reduce the need for trainers who work one-on-one or with small groups. The web-based training seems the most feasible, except for the current crop of elderly, many of whom do not use the Internet.

Effective training need not be specifically address memory. Non-specific mental stimulation can improve memory capability, because whatever affects the brain affects the brain’s ability to remember things. Especially promising are training programs that train people to be more attentive, to have more positive attitudes about their memory ability, reduce anxiety and stress, and require learners to apply memory techniques to everyday mental tasks.¹ When benefits from memory training persist after the training, researchers assume it is because the trainees are still using the techniques they have learned. Method-of-loci and peg-word systems are extremely powerful, but it is hard to get people to create new habits of thinking and memorization. Even so, memory training produces other lasting effects that benefit memory irrespective of the explicit use of techniques. One of these effects is actual re-wiring of the brain, which intense learning is known to produce.

Many sites on the Web focus on teaching people about mental fitness in general, which as I just said, has collateral benefit on memory capability. One site I recommend, and have posted to, is Sharp Brains (http://sharpbrains.com/). Among the better known Web training programs are Brainware Safari and Lumosity (I have no conflict of interest here). Using “brain fitness” as search words in Google or Bing will identify many other sites that I am not familiar with.

Recently, a new three-dimensional videogame system, “NeuroRacer” that reportedly works even for older adults has been developed at the University of California, San Francisco.[2] In this game, a user navigates a race car along a winding track and hits a button on a controller whenever a green circle appears, making the response as quickly as possible. This task forces concentration and trains the brain to switch operations rapidly and accurately.

In a recently published test of the NeuroRacer’s effects on older adults, people aged 60 to 85 were trained on the game for 12 hours, spread over a month. Without training, the researchers found a clear age-related decline in performance in the game. After training on the game, the seniors performed on the game better than untrained 20-year olds, and the benefit lasted at least six months.

Popular press reports and numerous blogs of this study have attributed the benefit to the value of multi-tasking. I contend that multi-tasking is harmful for memory and, moreover, that the benefit of NeuroRacer is not multi-tasking training as such but rather the training it provides for attentiveness and executive control.  It is perhaps not surprising that such good effects were seen in older folks. A typical problem in aging is a loss in ability to focus, and thus training that increases attentiveness would be likely to have conspicuously beneficial effects.

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[1]Rebok, G. W., Carlson, M. c., and Langaum, J. B. S. (2007). Training and maintaining memory abilities in health older adults: traditional and novel approaches. J. Gerontology. 62B (Special Issue): 53-61.

[2]Anguera, J. A. et al. (2013). Video game training enhances cognitive control in older adults. Nature 501: 97-101.

People frequently ask me “What’s the best way to improve my memory? (or … my child’s memory? … my elderly parent’s memory?). The answer most commonly given is to use memory aids, that is, mnemonic devices such as associating mental images of new information with images of already learned images that serve as pegs on which to hang new information. I explain these devices in great detail in both of my books, “Memory Power 101” and “Better Grades, Less Effort.”

Mnemonics are essential if you want to become a “memory athlete” and show off prodigious feats of memory. After you have used such mnemonics for a while, some of the benefit persists long after you quit using such mnemonics because the brain has been trained to be more facile and imaginative in making associations.

But for real-world practicality, it is hard to beat the usefulness of thinking about what you are trying to remember. Thinking unifies the essential elements of learning, which I view as follows:

Knowledge → Understanding → Creative Insight

When people try to acquire knowledge, they of course must remember it, which they usually attempt by mentally repeating it again and again. This rote process is the least effective way to remember. When you think about what you are trying to remember, your efforts to understand it actually constitute rehearsal in meaningful ways. Attempts to understand include associating and cross checking the new with your understanding of what you already know, thinking about what else might be relevant, reflecting on the merits of the new information, and self-examination of your level of understanding. Then, as understanding is gained, you become poised for creative insight, making application of the new information for your own needs and purposes. In the process, you might even think of things about the new information that others have not discerned. This process automatically creates mental associations that not only cement the new information in memory but also integrate it with all the things you already know as well as perhaps even generating ideas that nobody else has thought of.

The biological basis behind this thinking process of memory rehearsal is now being confirmed. The original basis of the idea comes from suggestion some 20 years ago that multiple areas of brain participate in formation of memory.[1]Thinking engages multiple areas of brain and, when performed on what you are trying to remember, strengthens the memory representation in the brain areas that are creating the engram.

Some recent support for multiple-area formation of memory includes a recent brain-scan study of male and female college students during consolidation of a recent fear-induced experience revealed increased activity in multiple brain areas (amygdala, parahippocampus, insula, thalamus, ventromedial prefrontal cortex, and anterior cingulate cortex) during a resting state lasting 10 minutes immediately after the conditioning.[2]“Rest” occurred immediately after responding to the fear-inducing stimulus and probably involved a process of reflection on the learning task or an equivalent subconscious process.

Decreased activity occurred in the striatum (caudate, putamen). This decrease may have occurred because this area of brain includes the positive reinforcement (reward) system, and fear conditioning is aversive, not rewarding.

I should add that the extensiveness of brain areas participating in thinking and its associated memory consolidation was surely under-estimated. MRI brain scans measure metabolism, which is not a direct index of the nerve impulse signaling required for processing learning events.

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[1]Squire, L. R. (1992) Declarative and non-declarative memory: multiple brain systems supporting learning and memory. J. Cognitive Neuroscience. 4 (3):232-243 Posted Online December 13, 2007.(doi:10.1162/jocn.1992.4.3.232)

[2]Feng, T., Feng. P., and Chen, Z. (2013). Altered resting-state brain activity at functional MRI during automatic memory consolidation of fear conditioning. Brain Res. 2013 Jul 26;1523:59-67. doi: 10.1016/j.brainres.2013.05.039

People are constantly exposed to stressful situations. These may be physical (like participating in marathons, being exposed to radiation, and, perhaps surprisingly, exposed to sedatives or anesthetics). But stress can also be mental, wherein we become anxious and worried over certain events, existing or anticipated. Whether physical or mental, stress activates a brain network involving most directly the hypothalamus, the pituitary gland, and the adrenal cortex to release stress hormones. Such hormones include several cortisone-like compounds called glucocorticoids, and the most prominent one in humans is cortisol.

Glucocorticoids have profound effects on both body and brain. Regulation of glucocorticoids is accomplished by the brain, and learning experiences have profound effects on this control system. Most of what was initially known about glucocorticoids was their effect on the body. I had the great thrill of visiting the pioneer in this field, Hans Selye, in his laboratory complex at the University of Montreal. He had a whole room full of medals, awards, and honorary doctorate diplomas. He won practically every research accolade there was, except the Nobel Prize, one of several grievous slights by the Nobel committee. Dr. Selye wrote an autobiography for my book, Discovery Processes in Modern Biology.

Effects on the Body

Selye’s research led him to formulate the widely accepted concept of the glucocorticoid system as accounting for a “General Adaptation Syndrome,” which basically explained how the brain and body respond to stress. He discovered that glucocorticoids are “Goldilocks” compounds. That is, a little doesn’t do much, a lot is damaging, and intermediate levels are “just right.”

A moderate amount of cortisol is what is normally released every morning before you awaken. By the way, this is the reason surgeons want to operate early in the morning. This release helps prepare the body for the day’s activities by mobilizing blood glucose, typically by breaking down fat and, if needed, protein stores. Glucose is especially important for the brain, which has huge demands for energy, and which can only burn glucose for energy. Neurons are energized and memory ability is enhanced. Another useful thing cortisol does is to reduce the release of cellular chemicals that cause inflammation.

However, the hormone also inhibits systems that channel resources for growth and reproduction, impairs bone formation, and inhibits the immune system. Basically, the idea is that glucocorticoids help brain and body to respond to temporary emergencies by assigning lower priority to other physiological needs.

The rub comes when stress is prolonged. Selye discovered that the beneficial adaptation to temporary stress cannot be sustained in chronic stress. The system becomes exhausted and control breaks down.[1]Under chronic stress, body muscle mass decreases because the system has been breaking down proteins in order to generate energy. Inflammation bathes cells in toxic chemicals. Infections increase because the immune system has been compromised. In obese people, glucocorticoid levels cumulatively increase in fat cells, increase fat deposits still further, and increase the likelihood of type 2 diabetes and cardiovascular disease.[2]

Effects on the Brain

In the case of brain, persistent high levels of glucocorticoid often causes depression. Memory ability is impaired. Brain degeneration and cognitive decline accelerate. Many neurons are actually killed. What I want to stress here is that chronic high levels of cortisone change the neural circuitry that regulates its release. In other words, the brain learns a new way of functioning if constantly bathed in high levels of cortisone.

Effects of Learning

Few people make the connection between glucocorticoid control and learning. The neuronal circuits that control hormone secretion learn from stressful experience, just as all neurons learn from whatever they experience. What neurons in the cortisol control circuit learn in chronic stress is that the usual controls can’t work any more.

A typical response to a repeated stress of a certain type (for example, constant quarrels with a spouse or repeated job failures) can be habituation. It’s like “tuning out.” Repeated exposure to the same stress teaches the neurons to stop responding as much as usual. Thus, there is less of the benefits that glucocorticoids provide.

At the same time, the hormone control system becomes hypersensitive to other stresses, especially unpredictable or especially severe stresses. The control system learns to over-react to everything other than the stress to which it has habituated. Now, the damaging effect of too much glucocorticoid becomes pervasive, both for body and brain.

Whether the brain learns stress-coping strategies depends on conscious over-ride of hyper-active responses to stress, because the neural system (the limbic system) that operates our emotions also regulates the glucocorticoid control system. We can not only reduce excessive glucocorticoid but also teach our brain better ways to deal with stress by doing the following:

·         Simplify and organize our life,

·         Do one thing at a time and finish it,

·         Find pleasure in the little things,

·         Learn to have a more positive attitude,

·         Laugh and be happy,

·         Suppress anxiety,

·         Be more rational and less emotional,

·         Develop supportive social relations,

·         Reduce exposure to stressors. 

For more on learning and memory in general, see Dr. Klemm’s new book, Memory Power 101, Skyhorsepublishing.com.

Photos courtesy of FreeDigitalPhotos.net, by Artur  84 and Ambro

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[1] Herman, James P. 2013. Neural control of chronic stress adaptation. Frontiers in Behavioral Neuroscience. August 8. Doi: 10.3389/fnbeh.2013.00061

[2] Vogelzangs N. et al. 2009. Late-life depression, cortisol, and the metabolic syndrome. Am J Geriatr Psychiatry. 2009 Aug;17(8):716-21. doi: 10.1097/JGP.0b013e3181aad5d7.

I just attended a “Laughter is Good Medicine” seminar put on by a local hospital. The speaker pointed to evidence showing that laughing has such good effects as:

·         Reduce blood pressure

·         Lower blood glucose

·         Dull pain

·         Alleviate stress and anxiety

·         Improve feeling of well being

and it even burns substantial calories.

I suspect humor also improves longevity, though I only have anecdotal and presumptive evidence for that. But the evidence seems hard to dismiss. Think about how long so many classic stand-up comedians of the

preceding generation lived.

Most of these comedians were actively performing right up to their last days. Here is a listing of comedians most people in my generation will recognize and their age when they finally died.

Bob Hope, 100

George Burns, 100

Phyllis Diller, 95

Milton Berle, 94

Henny Youngman, 92

Victor Borge, 91

Dick Van Dyke, 88 (still alive)

Jimmy Durante, 87

Jerry Lewis, 87 (still performing)

Bea Arthur, 87

Groucho Marx, 87

Jonathan Winters, 86

Jack Paar, 86

Red Skelton, 84

Bob Newhart, 84 (still performing)

Soupy Sales, 83

Rodney Dangerfield, 83

Mel Blanc, 81

Johnny Carson, 80

Jack Benny, 80

These comedians obviously had good memories, because even in their old age they could spout a steady stream of jokes from memory without a teleprompter. To have a good memory, you have to have a healthy brain, and a healthy brain often is healthy because the body is healthy. Healthy bodies live longer.

Let’s also remember that some of these people led a hard life, mostly on the road, in an era when people in general did not live that long.

One thing is for sure. Whether or not humor makes you live longer, it surely does make you live happier.

In an earlier post, I reviewed research showing that seniors compensate for any loss of memory ability by having developed learning and memory schemas over the years. Such schemas are ingrained strategies and ways of efficient learning that improve with experience and age.

Now I have come across recent research that shows another age-developed skill: improved decision-making ability. Teenagers are notorious for poor decision-making. Of course that is inevitable, given that their brains are still developing and they have had relatively little life experience to show them what works and what doesn’t. Unfortunately, what doesn’t work often has more emotional appeal, and most of us at any age are more susceptible to our emotions than to cold, hard logic.

Seniors also are prone to poor decision-making if senility has set it. Unscrupulous people take advantage of such seniors because a brain that is deteriorating has a hard time making wise decisions.

In between teenage and senility is when the brain is at its peak for good decision making, especially improving as one gets older. Some Eastern cultures venerate their older people as generally being especially wise. After all, it you live long enough, and are still mentally healthy, you ought to make good decisions because you have a lifetime of experience to teach you what future choices are likely to work and which are not.

Much of that knowledge comes from learning from one’s mistakes. On the other hand, some people, especially the young, can’t seem to learn from their mistakes. In any case, the best strategy of all is to learn from somebody else’s mistakes so you don’t have to make them yourself.

Learning from your mistakes can be negative if you fret about it. Learning what you can to avoiding repeating a mistake is one thing, but dwelling on it erodes one’s confidence and sense of self worth. I can never forget the good advice I read recently from, of all people, T. Boone Pickens, who has lost and regained fortunes several times. He was quoted in an interview as saying that he was able to re-make his fortune on multiple occasions because he didn’t dwell on the failures. He credited that attitude to his Oklahoma State basketball coach, who told the team after each defeat, “Learn from your mistakes, but don’t dwell on them. Learn from what you did right and do more of that.”

A key reason seniors make better decisions is that they have a richer store of knowledge and experience. Any choice among alternative options is affected by how much information for each option the brain has to work on. When the brain is consciously trying to make a decision, this often means how much information the brain can hold in working memory. Working memory is notoriously low-capacity, so the key becomes remembering the sub-sets of information that are the most relevant to each option. People are more likely to remember items they value and to forget low-value items.[1]

It turns out, apparently, that older people are more likely to remember the most useful information and thus make better conclusions and decisions. The National Institute of Aging began funding decision-making research in 2010 at Stanford University’s Center on Longevity. Results of their research are showing how older people often make better decisions than younger people.[2]^,[3]

As one example, older people are more likely to make rational cost-benefit analyses. Older people are more likely to recognize when they have made a bad investment and walk away rather than throwing more good money after bad.

A key factor seems to be that older people are more selective about what they remember. For example, one study from the Stanford Center compared the ability of young and old people to remember a list of words. Not surprisingly, younger people remembered more words, but when words were assigned a number value, with some words being more valuable than others, older people were better at remembering high-value words and ignoring low-value words. It may be that older people selectively remember what is important, which could explain why they make better decisions.

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[1] Castel, A. D., Rhodes, M. G., McCabe, D. P., Soderstrom, N. C., Loaiza, V. M. (2012). The fate of being forgotten: Information that is initially forgotten is judged as less important. Quarterly Journal of Experimental Psychology, 65, 2281-2287.

[2] Samanez-Larkin, G.R., Wagner, A.D., Knutson, B. (2011) Expected value information improves financial risk taking across the adult life span. Social Cognitive and Affective Neuroscience, 6(2), 207–217

[3]Carr, Dawn (2013). Why older minds make better decisions. Forbes. http://www.forbes.com/sites/nextavenue/2013/04/29/why-older-minds-make-better-decisions/

For more good advice on improving learning and memory abilities, see Dr. Klemm’s new book, Memory Power 101, Skyhorse Publishing.

Do you consciously monitor your working memory? That’s the limited-capacity memory you use when looking up a phone number, for example. If you fail to keep the numbers actively in mind while dialing, you may have to look up the number again. In other words, do you check yourself to see if you are still paying attention to what is in your working memory? Is your mind wandering away from what you are trying to hold in working memory? The cure is to deploy your brain’s innate capacity for executive control over working memory.

For more complicated memory chores than dialing a phone number, are you consciously aware of updating what is in your working memory at a given moment with new information? Do you think about being able to recall information you have just received—as when you are reading? Or do you ever willfully suppress what is in your working memory—as for example, expunging an unpleasant thought.

These questions deal with how well you are consciously aware of the likelihood you can recall what you are experiencing. I suspect that most of us exert some conscious executive control over working memory, but not nearly as efficiently as we could or should. Does it matter? Well yes, because controlling what is in your working memory affects the ongoing thought processes that are using the information that is in working memory. Moreover, how well you monitor your working memory affects how well the information registers in your brain and how well it can become consolidated into a more lasting memory.

I explain the consolidation process and ways to enhance it in my book, Memory Power 101.

Executive control of memory is relatively new in memory research, but one group reports studies suggesting that such research will prove fruitful. A year or so ago, this group’s poster presentation at the Society of Neuroscience meeting intrigued me, and I am delighted that the work has now been formally published.

One of their experiments evaluated listeners’ ability to monitor their moment-to-moment working memory storage capacity as new information arrived. As they listened to recorded word lists, experimenters told the subjects to pause the input at the maximum point that would still allow them for perfect real-time memory recall. That is, they pressed a key to pause the input of words in the list at the latest point at which they believe they would have perfect recall. Interestingly, all subjects paused the recording consistent with their known working memory span, as had been determined in pre-experiment testing. In a follow-up experiment, experimenters reduced the sound volume of the word list so that more effort had to be exerted to perform the task. Under these conditions, subjects were much less accurate in matching their listening to their natural working memory capacity and thus their learning was not optimal.

Obviously, such results suggest that making tasks more difficult can degrade thinking and learning. Teachers and professors who speak softly or with foreign accents should take note. Whatever benefit accrues from the challenge to pay better attention under difficult situations is offset by limitations in working memory storage capacity. Examples of degrading influences in addition to sound volume in listening to information include:

Listening is made more difficult by:

·         Extraneous noise

·         Unfamiliar speech accents

·         Speaking too rapidly

·         Speaking too softly

·         Simultaneous presence of visual stimuli that conflict or distract

·         Irritating or distracting mannerisms of the speaker

Reading is made more difficult by:

·         Font and page design selection

·         Convoluted syntax, awkward sentence structure

·         Unfamiliar vocabulary

·         Distracting visuals

·         Wordiness, poor grammar

·         Poor reading technique (tracking with finger movements, random eye fixations, small fixation span (a few letters or one word at a time)

In all situations, an important factor is whether the listener or reader has control over the speed of information presentation. Thinking and learning are compromised if a person has no control over chunking of information input and matching the input to their working memory storage capacity.

Another factor, not considered in this study, is the likelihood that people differ significantly in conscious executive control capability. We know, for example, that some people can hold focus much better than others can, and this certainly affects their ability to optimize working memory storage of information input.

Can working memory executive control be trained? There are already effective training protocols for expanding working memory capacity (as in the number of items you can hold in working memory). I suspect that we will soon see training programs to enhance executive control of working memory.

To summarize, you can optimize thinking and learning by willfully controlling the ease and convenience of information input as well as by how well you have developed a habit of conscious executive control.

Source:

Amichetti, N. M., Stanley, R. S., White, A. G., and Wingfield, A. (2013). Monitoring the capacity of working memory: executive control and effects of listing effort. Mem. Cogn. DOI: 10.3758/s113421-013-0302=0

School is ending for the year, and students surely welcome the break. But they will do well to think on how they learn to learn so that next Fall they can be more successful with less effort. Interesting how that reminds me of my e-book for students, Better Grades, Less Effort.

In my experience with students, both the college students I teach and the secondary students that teachers tell me about, the biggest weakness students have is that they either try to remember school material by rote memorization or have no strategy at all, relying on some kind of magical mental osmosis.

 Even among students who rely on rote memory, they generally lack much of a strategy for memorizing, relying on varying degrees of casual “looking over” the instructional material until they think they can remember it. Experiments show that students routinely over-estimate how much they remember and under-estimate the value of further study. Moreover, many educators at all levels have disdain for memorization, stating that we should focus education on teaching students to think and solve problems, as if you can think and solve problems without knowing anything. Too many teachers regard memorizing as old-fashioned and even destructive of enlightenment.

Disdain for memorization is a relatively new phenomenon in education. In ancient times, people took great pains and pride in memorizing huge quantities of information. The advent of printing greatly reduced the need to memorize history and cultural mores. In modern times, we have the Internet, where you can just Google what you need to know. So who needs to get brain-strain trying to remember things?

Now we have a book by Samuel Arbesman, The Half-Life of Facts: Why Everything We Know Has an Expiration Date, where he argues that there are no lasting facts. They all have a half life, that is, the number of years it takes to falsify half of what you think are facts. He argues that new “facts” are made all the time, often replacing what we had previously thought were facts. He argues we should just stop memorizing and look up whatever current facts we need on the Internet. But if there are no lasting facts, how are those you find on Google any more valid than those you memorize and can deploy in real time.

There are some serious errors in Arbesman’s position.

1.      Many facts are immutable; that is, they don’t have a half-life. Events in history did actually occur, and while revisionist writers of school history textbooks may change the reporting of those events, the facts remain true. Nixon covered up Watergate, Obama obfuscated Benghazi. The fact of DNA as a basis for heredity is not likely to change.

2.      Many facts that do change will not change in a given person’s lifetime and thus will be useful in daily living.

3.      The Internet is flooded with error, propaganda, and un-vetted assertions.

4.      You don’t always have Internet access.

5.      In many situations, it is not practical to look up what you need. Ever try to read or speak a foreign language where you have to look up most of the words? Ever try to use computer software where you have to repeatedly refer to the instruction manual?

6.      Expertise in any field of endeavor requires a great deal of memorized “facts.” And if you want to succeed in life, it pays to be an expert.

I can easily make a strong case for memorization, especially for schools. Here is a list supporting the importance of memorizing:

1.      Memorized information is always with you, even when you lack the time or access to sources where you could look it up.

2.      We think and solve problems with what is in working memory, which in turn is memory of currently available information or recall of previously memorized  information. The process of thinking is like streaming video on the Internet: information flows in as short frames onto the virtual scratch pad of working memory, successively replaced by new chunks of information from real-time or recalled memory. Numerous studies show that the amount of information you can hold in working memory is tightly correlated with IQ and problem-solving ability.

We think by shuttling small batches of information as we experience it or from memory onto a  virtual  scratchpad called working memory. These batches are shuttled  sequentially into our  processing networks ("thought engine"). How well we think depends on what is on the scratch pad. From Klemm, 2011. Atoms of Mind, Springer.

3.      Memorization provides exercise for the mind. This is the reason schools used to require students to memorize poems, Bible verses, famous speeches, etc. The true advantage of such exercise is that generates mental industriousness. Any teacher will tell you that many students today are mentally lazy. Memorization also trains the mind to pay attention and focus intensely. Such skill also seems to be lacking in many youngsters, which is most obvious in the growing number of kids diagnosed with ADHD.

4.      Memorization trains the brain to develop learning and memory schemas that facilitate future learning. Learning schemas develop as you acquire competence in an area—call it skill A. Now, when you need to learn a new and related skill, B, you mind says to itself, “I don’t know how to do B. But I do know how to do A, and some of that can be applied to learning B.” Memory schemas are memorized frames of reference and association, where having memorized fact A, you have an association handle for memorizing fact B.

5.      If you learn strategies for memorization, as opposed to the rote memory approach of looking information over repeatedly, you accelerate the ease, speed, and reliability of learning new things.

Bottom line: the more you know, the more you can know!

Regardless of where you stand on the importance of memory, most people believe that learning is a good thing. But what good is learning if you don’t remember it?

If you are convinced that you or your loved ones could benefit from better memory, many ways to do it are explained in my books, Better Grades, Less Effort (e-book for students) and Memory Power 101(paperback from SkyhorsePublishing.com). 

As each of us goes through life, we remember a little and forget a lot. The stockpile of what we remember contributes greatly to define us and our place in the world. Thus, it is important to remember and optimize the processes that make that possible.

People who compete in memory contests (“memory athletes”) have long known the value of associational cues (see my Memory Power 101 book). Neuroscientists have known for a long time about memory consolidation (converting short-term memory to long-term form) and the value of associational cues. But now, important new understanding is arising from a research lab at Northwestern that links cueing to “re-consolidation” and reveals new possibilities for optimizing long-term memory formation.

The underlying research approach is based on such well-established memory principles as:

1. When information is first acquired, it is tagged for its potential importance or value.
2. Such tagging is influenced by multiple factors such as repetition, attention, emotion, or purpose.
3. Valuable memories get preferentially rehearsed, either through conscious will or by covert (implicit) brain processes.
4. Rehearsal episodes reactive the memory and enhance long-term remembering because each re-consolidation episode builds on prior ones and strengthens the neural circuits that store the memory.
5. Effectiveness of recall during rehearsal is promoted by use of relevant cues, that is, information that was associated with the original learning material.
6. Such cues are effective, even when delivered during sleep.

The pioneering study involving sleep learning appears to have been done by John Rudoy and colleagues in 2009 [1}. They showed that people recalled locations of memorized objects better if they heard sounds associated with the locations during their sleep that had been earlier associated with the learning of object locations. The basic finding was replicated in a follow-up study [2].

Most recently, a study by another group also confirmed and extended this concept of using cues during sleep to promote memory formation.The study involved 60 people in their early 20s, screened for good memory ability.[3]All subjects participated in a four-hour learning period beginning in late morning. The learning consisted of 72 images placed in specific locations on a tile-like screen and presented one at a time. As each image appeared a corresponding sound was associated, intended to serve as a learning cue. For example, a dog picture would be associated with barking, cat with meow sound, etc. To create a value bias, each image had a superimposed number representing how important it was to remember this item and its location upon later testing. Subjects were given financial reward for how well they remembered, and thus remembering high-value images was a priority. Half of the images had high value assignments, while the rest had low values.

 Subjects were assigned to four groups:  

1. Groups 1 and 2 were tested to see how well they could remember where each object had appeared during the learning phase. They then took a 90 min nap while their EEGs were recorded. Half of these subjects heard white noise while the other have was presented the original sound cues of low-value images during non-REM sleep at a level that did not cause awakening. At the end of the nap, recall was again tested.
2. The procedure in two other groups was similar except that these subjects did not nap. One of these groups watched a movie during the 90 minutes after the learning session, while the other group listed to the low-value sound cues while performing a working memory task.

Not surprisingly, the studies revealed that high-value images were remembered better, irrespective of whether or not a nap was taken. The practical point is that we remember better the things we value and find to have positive reward value. This reminds me of the sage saying that T. Boone Pickens repeated from his basketball coach, who told players after each game: “Don’t dwell on your mistakes. Think about what you did right and do more of that!”

In the study, half of the low-value associations were rescued by cueing during wakefulness and all of them were rescued by cueing during sleep, even though only half of the images were cued. Notably, the best effects occurred during the deepest stage of sleep. No explanation was given to explain the sleep benefit, but I suspect it is because the sleeping brain is not distracting itself with irrelevant thoughts. This is consistent with the finding that low-value memories were not rescued well during REM sleep, when the brain is busily engaged in dreaming. The REM-sleep finding is at variance with other studies that reported a memory consolidating benefit of REM sleep. Apparently, the test conditions make a difference and more research is needed here.

Low-value associations were preferentially forgotten in the group that was not allowed to nap. This likely signifies that a brain busily engaged with other thoughts is less able to selectively consolidate memories, and only high-value items are likely to survive. This accords with the long-held theory that distractions and multi-tasking interfere with memory consolidation.

In summary, memory optimization would seem to require one to:

1.    Create associations that can serve as memory cues.

2.    Place a high value on the cues and their targets.

3.    Repeatedly present the cues and replay the initial information. When awake, present the cues in self-test mode. When asleep, even better results would obtain if cues were presented at a level that does not cause awakening during the early night sleep when sleep is deepest and there is little dreaming.

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1. Rudoy, J. D., Voss, J. L., Westerberg, C. E., Paller, K. A. (2009). Strengthening individual memories by reactivating them during sleep. Science. 326: 1079.

2.. Antony, J. W, Gobel, E. W., O’Hare, J., K., Reber, P. J., and Paller, K. A. (2012). Cued memory reactivation during sleep influences skill learning. Nat. Neurosci. 15: 1114:1116.

2. Oudiette, D., Antony, J. W., Creery, J. D., and Paller, K. A. (2013) The role of memory reactivation during wakefulness and sleep in determining which memories endure. J. Neurosci. 33(15): 6672-6678.

Don't forget to check my memory e-book, Better Grades, Less Effort, 

for only $2.99 at Smashwords.com.

Physical exercise can rehabilitate bodies that have grown soft and flabby. Can mental exercise rehabilitate brains that have deteriorated because of disease or age? Maybe.

A published scholarly review has examined the research literature on this issue and arrived at several useful conclusions:

1.      Focus, Reduce Distractions. The two common causes of forgetting, in both normal people and those with impaired memory, are a) failure to register new information effectively, and b) interference from conflicting sensations and thoughts.

2.      Customize the Rehabilitation Needed. Rehab need to take into account the type of memory therapy and the cause and severity of the impaired memory capability.

3.      Learn in Small, Frequently Repeated Chunks. New information has to be re-packaged for memory-impaired people so that it is in simple, concrete form, in small chunks, and repeated frequently — with patients required to re-state the information and make explicit associations with what they already know. (Notice how this sounds like the way one needs to teach young children).

4.      Practice Attentiveness. Attentiveness to new information can be enhanced by self-cueing, wherein patients remind themselves to be more attentive at crucial moments. This can even be done by creating a conditioned reflex in which a cue signal conditions greater attentiveness. (Notice how this sounds like how you “clicker” train dogs).

5.      Uses Mnemonics. Mnemonic tips and tricks can help. This includes using acronyms, rhymes, stories, and constructing mental images.

6.      Find Ways to Compensate. Even in patients with severe impairments, some aspects of memory, such as subliminal or implicit memory, may have been spared and can be exploited to compensate for the lost ability.

7.      Spread Rehearsals Over Time. Memory rehearsal is more effective if it is spread out over time rather than bunched into a few closely spaced sessions.

8.      Manipulate the Cues. Be more aware of cues you are using. A “vanishing clues” approach can help. For example, in a rehearsal session, cued retrieval might begin with cueing the first three letters of a target word, then repeating later with two, then  one, and eventually no letter cues.

9.      Minimize Error, Lest you Learn the Errors. Trial-and-error learning is generally less effective than learning conditions that minimize error, because error responses can get stored as memories that compete with the right answers. In short, it is better to not know than to generate wrong answers.

10.  Use Memory Crutches. Using external memory aids (sticky notes, wall charts, notebooks, etc.) should help, bearing in mind, however, that using such aids may themselves be a memory task. It is like having a schedule calendar and forgetting to check the calendar. Smart phones and radio paging devices (“NeuroPage”) can be especially helpful because they remind the patient when to check on the stored information. In some patients, repeated use of such aids develops a habit for target tasks and these may even generalize to certain non-target tasks.

These ten approaches are some of the same approaches that work especially well in people with normal memory capabilities. To make them work in patients with impaired memory just takes more effort, patience, and time.

Source: Ptak, R., Van der Linden, M., and Schneider, A. 2010. Cognitive rehabilitation of episodic memory disorders: from theory to practice. Frontiers in Human Research. 4 (57): 1-11. doi: 10.3389/fnhum.2010.00057.